Beclo - Nasal Spray 200 Doses

Seasonal and perennial allergic rhinitis; vasomotor rhinitis.

Trade name: Beclo

Beclo

Composition: Each 100 ml of spray contains:

Beclomethasone dipropionate monohydrate 43.45

Equivalent to Beclomethasone dipropionate 42 mg

Auxiliary components:

Avicel, Twain 80, benzalkonium chloride, edetate disodium, anhydrous disodium hydrogenorthophosphate, purified water.

Properties: GCS for nasal use.

Beclomethasone dipropionate is a prodrug and has a weak affinity for glucocorticoid receptors. Under the influence of esterases, it turns into an active metabolite beclomethasone-17-monopropionate, which has a pronounced local anti-inflammatory effect by reducing the formation of chemotaxis substance (effect on delayed-type allergic reactions). By suppressing the production of metabolites of arachidonic acid and reducin the release of inflammatory mediators from mast cells, it inhibits the development of an immediate allergic reaction.

Prevents marginal accumulation of neutrophils, reduces inflammatory exudation and production of lymphokines, inhibits the migration of macrophages, reduces the intensity of infiltration and granulation processes, and the formation of chemotaxis substance. Reduces swelling of the nasal mucosa, mucus production. Improves mucociliary transport.

It has no mineralocorticoid activity, practically does not have a resorptive effect.

Indications: Seasonal and perennial allergic rhinitis; vasomotor rhinitis.

Method of administration and dosage: Adults and children over 12 years old:

2 doses (injections) in each nasal passage 2 times / day.

The maximum daily dose is 400 mcg. The d dose can be divided into 2-4 doses.

Children aged 6 to 12 years: the initial dose is 1 dose (injection) in each nasal passage 3 times / day.

The maximum daily dose is 400 mcg. The daily dose can be divided into 2-4 doses.

When the therapeutic effect is achieved, the drug is canceled, gradually reducing the dose.

Elderly patients do not need dose adjustment.

Contraindications: Hemorrhagic diathesis; frequent nosebleeds; respiratory tuberculosis; fungal infections; viral infections; children under 6 years old; I trimester of pregnancy; hypersensitivity to beclomethasone and excipients of the drug used.

Carefully

Amoebiasis; glaucoma; severe liver failure; hypothyroidism; recent myocardial infarctio ulceration of the nasal septum; after recent surgery in the nasal cavity or nasal injuries; in the Il and Ill trimesters of pregnancy; lactation period (breastfeeding).

Precautions: Avoid contact with eyes.

Relief of rhinitis symptoms usually appears within a few days of starting treatment.

Patients who may have a decrease in immunity against the background of GCS therapy should be warned of the danger of contact with patients with certain infections (for example, chickenpox, measles) and the need to consult a doctor in case of such contact. This is especially important for children.

Because beclomethasone slows down wound healing, patients who have recently undergone an injury or nasal surgery should not use the drug until the wounds have healed completely.

Side effects: Allergic reactions: rarely — skin rash, urticari angioedema.

From the side of the nervous system: rarely — a violation of the olfactory and gustatory sensations, drowsiness, headache, dizziness.

From the side of the organ of vision: unknown — increased intraocular pressure, incl. glaucoma, cataract (with prolonged use), conjunctival hyperemia, decreased vision.

From the respiratory system: rarely — dryness and irritation of the nasopharynx, sneezing, burning, nasal congestion, nosebleeds, atrophy of the nasal mucosa, cough, rhinorrhea; very rarely — ulceration of the nasal mucosa, perforation of the nasal septum (usually in patients who have previously undergone surgery in the nasal cavity).

Others: rarely — myalgia, candidiasis of the oral cavity and upper respiratory tract (with prolonged use and / or in high doses (more than 400 mcg / day)); unknown — with prolonged use, it is possible to develop adrenal insufficiency, a decrease in the growth rate in children, a decrease in bone mineral density

Storage method: At a temperature not higher than 25 degrees.

Packaging: 200 doses — aluminum cans with a plastic dosing valve-spray system for nasal use cardboard packs.