Flix - 50 mcg / Dose Nasal Spray 20 ml

Treatment of perennial and seasonal allergic rhinitis, including hay fever (hay fever): — pain, feeling of pressure in the paranasal sinuses; nasal congestion, sneezing, itching in the nose; — lacrimation.

Tradename: Flix

Composition: Each spray dose contains:

Fluticasone propionate 50 mcg

Auxiliary components:

dextrose, avicel RC591 (microcrystalline cellulose, sodium carmellose), phenylethanol, benzalkonium chloride, polysorbate, hydrochloric acid, purified water.

Properties: GCS for intranasal use. It has a pronounced anti-inflammatory effect. With intranasal administration, there is no systemic effect, practically does not inhibit the hypothalamicpituitary-adrenal system.

The anti-inflammatory effect of fluticasone propionate is realized as a result of its interaction with glucocorticoid receptors. Suppresses the proliferation of mast cells, eosinophils, lymphocytes, macrophages, neutrophils. Fluticasone propionate reduces the production of inflammatory mediators and a number of biologically active substances (including histamine, prostaglandins, leukotrienes, cytokines) during the early and late phases of an allergic reaction. Has a fast anti-inflammatory effect on the nasal mucosa. Antiallergic effect appears within 2-4 hours after the first application. Reduces sneezing, itchy nose, rhinorrhea, nasal congestion, sinus discomfort and pressure around nose and eyes. In addition, it relieves eye symptoms associated with allergic rhinitis.

Indications: Treatment of perennial and seasonal allergic rhinitis, including hay fever (hay fever): — pain, feeling of pressure in the paranasal sinuses; nasal congestion, sneezing, itching in the nose; — lacrimation.

Method of administration and dosage: Adults and children over 12 years old:

1st week: 2 injections into each nostril 1 ti day (200 mcg / day);

from the 2nd week to 3 months: 1 or 2 injections into each nostril 1 time / day (IOO200 mcg / day).

The maximum daily dose is 200 mcg / day (no more than 2 injections into each nostril).

The maximum course of treatment is 3 months per year.

Children aged 4 to 12:

1 injection into each nostril 1 time / day (100 mcg / day). Do not exceed the recommended dose (100 mcg / day). In children aged 4 to 12 years, the drug should be used for the shortest possible period of time necessary to achieve control over the symptoms of the disease. It is necessary to contact the attending physician if the child needs to use the drug for a period of time exceeding 2 months a year.

The maximum daily dose is 100 mcg (no more than 1 injection and each nostril).

Contraindications: - increased sensitivity to fluticasone propionate

and other components of the drug;

children up to 4 years old; recent injury to the nose or surgery and nasal cavity. Precautions: Before using the drug, the patient should consult a doctor in the following cases:

taking medications for the treatment of HIV infection, such as ritonavir; taking GCS for the treatment of bronchial asthma, allergies, skin rashes; Taking medications to treat fungal infections such as ketoconazole

taking other powerful inhibitors of the isoenzyme CYP3A, for example, itraconazole; if you have glaucoma or cataracts.

Use with caution if you have a nasal or sinus infection. It should be borne in mind that infectious diseases of the nose require appropriate treatment, but are not a contraindication to the use of Flix@ nasal spray.

Side effects: From the nervous system: often — headache, a feeling of unpleasant taste and smell. Headache, unpleasant taste and odor have also been reported with other nasal sprays.

From the respiratory system: very often epistaxis; often — dryness of the mucous membrane in the nasal cavity and pharynx, irritation of the mucous membrane in the nasal cavity and pharynx (these adverse reactions, as well as nosebleeds were observed when using other intranasal.

Storage method: In a cool dry place at a temperature not exceeding 30 degrees.

Packaging: The cardboard box holds a 20ml bottle, paper