Imigran - 50 mg 2 Tablets

Migraine attack with or without aura.

Tradename:

Imigran

Imigran

Compound:

Each tablet contains:

sumatriptan 50 mg

Auxiliary components:

Lactose, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, purified water.

Properties:

Sumatriptan is a specific selective agonist of 5-HT1-serotonin receptors, localized mainly in the blood vessels of the brain, and their stimulation leads to a narrowing of these vessels. Does not affect other subtypes of 5-HT-serotonin receptors (5-HT2-7). Activates the sensitivity of the trigeminal receptors. The therapeutic effect usually occurs within 30 minutes after ingestion.

Indications:

Migraine attack with or without aura.

Dosage and administration:

Inside, the tablet should be swallowed whole with water. Treatment should be started as early as possible when a migraine attack occurs. The recommended dose is 50 mg, if necessary, 100 mg.

If the symptoms of migraine do not disappear and do not decrease after taking the first dose, then the drug is not used again to stop the same attack.

For the relief of subsequent attacks (with a decrease or disappearance of symptoms, and then resumption), a second dose can be taken within the next 24 hours, provided that the interval between doses is at least 2 hours.

The maximum daily dose is 300 mg.

Contraindications:

— hemiplegic, basilar or ophthalmoplegic forms of migraine;

— FIBS or the presence of symptoms suggesting its presence;

— history of myocardial infarction;

— pharmacologically uncontrolled arterial hypertension;

— occlusive diseases of peripheral vessels;

— stroke or transient cerebrovascular accident (including history);

— severe violations of the liver and kidneys;

— simultaneous administration with ergotamine or its derivatives and within 24 hours after their administration;

— use while taking monoamine oxidase inhibitors or earlier than 2 weeks after discontinuation of these drugs;

— age up to 18 and over 65 years (efficacy and safety have not been established);

-pregnancy;

— breastfeeding (breastfeeding is possible no earlier than 24 hours after taking the drug);

— congenital galactosemia, glucose / galactose malabsorption syndrome, congenital lactose deficiency;

— hypersensitivity to any of the components of the drug.

Precautionary measures:

Do not use to prevent a migraine attack.

Patients at risk from the cardiovascular system do not start therapy without a preliminary examination (women in the post-menopausal period, men over the age of 40, people with risk factors for developing coronary artery disease). Before prescribing sumatriptan to patients with newly diagnosed or atypical migraine, other potentially dangerous neurological diseases should be excluded. After taking sumatriptan, pain and a feeling of tightness in the chest may occur. The pain may be intense and radiate to the neck. If there is reason to believe that these symptoms are a manifestation of coronary artery disease, it is necessary to conduct an appropriate examination.

Side effects:

From the nervous system: often — dizziness, drowsiness, sensitivity disorders, including parasthesia and decreased sensitivity.

From the side of the cardiovascular system: often — a transient increase in blood pressure (observed shortly after taking the drug), hot flashes.

On the part of the respiratory system and respiratory organs: often — dyspnea, mild, transient irritation of the mucous membrane or a burning sensation in the nasal cavity or throat, epistaxis.

From the gastrointestinal tract: often — nausea, vomiting.

From the musculoskeletal system and connective tissue: often — a feeling of heaviness (usually transient, can be intense and occur in any part of the body, including the chest and throat).

General and local reactions: often — pain, a feeling of cold or heat, a feeling of pressure or tightness (usually transient, can be intense and occur in any part of the body, including the chest and throat), weakness, fatigue (usually mild or moderate, transient).

Storage method: At a temperature not higher than 30 degrees.

Package: Tablets 50mg:

The cardboard box contains a blister of 2 tablets.