Levohistam - 5mg/10ml Syrup 120ml

treatment of symptoms of year-round (persistent) and seasonal (intermittent) allergic rhinitis and allergic conjunctivitis, such as itching, sneezing, nasal congestion, rhinorrhea, lacrimation, conjunctival hyperemia;

pollinosis (hay fever);

hives;

other allergic dermatoses, accompanied by itching and rashes.

Trade name: Levohistam

Compound: 5 ml of syrup contains 2.5 mg of levocetirizine dihydrochloride.

Auxiliary components: Sorbitol 70%, sodium citrate, sucralose, sodium methyl paraben, sodium propyl paraben, strawberry flavor, purified water.

Properties: Levocetirizine is the R-enantiomer of cetirizine; competitive histamine antagonist; blocks histamine H1 receptors, the affinity for which is 2 times higher than that of cetirizine. Levocetirizine has an effect on the histamine-dependent stage of allergic reactions; reduces the migration of eosinophils, reduces vascular permeability, limits the release of inflammatory mediators. Prevents the development and facilitates the course of allergic reactions, has an antiexudative, antipruritic effect; practically no anticholinergic and antiserotonin action. In therapeutic doses, it practically does not have a sedative effect.

Indications: treatment of symptoms of year-round (persistent) and seasonal (intermittent) allergic rhinitis and allergic conjunctivitis, such as itching, sneezing, nasal congestion, rhinorrhea, lacrimation, conjunctival hyperemia;

pollinosis (hay fever);

hives;

other allergic dermatoses, accompanied by itching and rashes.

Mode of application: The drug is taken orally during a meal or on an empty stomach. The daily dose is recommended to be taken in 1 dose.

children 6-11 years old: the daily dose is 2.5 mg (1 tsp) 5 ml.

The maximum daily dose is 5 mg.

Adults and children over 12 years old

Daily dose 5mg (10ml — 2h/l) once in the evening.

Dose for children from 6 months to 5 years:

It is recommended to take 1.25 mg (1/2 teaspoon of syrup) 2.5 ml once in the evening

Contraindications: hypersensitivity to the active substance, cetirizine, hydroxyzine, any piperazine derivative or any other excipient of the drug;

lactase deficiency, lactose intolerance, glucose-galactose malabsorption; end-stage renal disease,

Carefully: Caution is required in the following conditions: chronic renal failure (correction of the dosing regimen is necessary); in elderly patients (with an age-related decrease in glomerular filtration), while using alcohol, prostatic hyperplasia, as well as in the presence of other predisposing factors for urinary retention, since levocetirizine may increase the risk of urinary retention; when administered to pregnant women and during breastfeeding.

Precautionary measures: Levocetirizine may cause increased drowsiness, therefore, the drug may affect the ability to drive a car or operate machinery. During the period of taking the drug Levocetirizine, it is advisable to refrain from performing potentially hazardous types of work that require increased concentration of attention and speed of psychomotor reaction (including driving a car and operating mechanisms).

Side effects: From the immune system: hypersensitivity reactions, including anaphylaxis.

From the side of metabolism: increased appetite.

On the part of the psyche: anxiety, aggression, agitation, depression, hallucinations, insomnia, suicidal thoughts.

From the nervous system: convulsions, thrombosis of the sinuses of the dura mater, paresthesia, dizziness, fainting, tremor, dysgeusia.

On the part of the organ of hearing: vertigo.

On the part of the organ of vision: blurred vision, blurred vision, inflammatory manifestations.

From the side of the cardiovascular system: angina pectoris, tachycardia, palpitations, jugular vein thrombosis.

From the respiratory system: shortness of breath, increased symptoms of rhinitis.

From the digestive system: nausea, vomiting, diarrhea.

Hepatobiliary disorders: hepatitis, changes in liver function tests.

From the urinary system: dysuria, urinary retention.

On the part of the skin and soft tissues: angioedema, persistent drug erythema, itching, rash, urticaria, hypotrichosis, cracks, photosensitivity.

From the musculoskeletal system: muscle pain, arthralgia.

General disorders: peripheral edema, weight gain.

Miscellaneous: cross-reactivity.

If any of the side effects listed in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Storage: Keep out of the reach of children, in a dark place, at a temperature not exceeding 25 ‘.

Package: The cardboard box contains a 120 ml glass jar and paper instructions.