Diclac ID

Articular syndrome (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout) Pain in the spine, neuralgia, myalgia, arthralgia, pain syndrome and inflammation after operations and injuries, pain syndrome with gout, migraine, algomenorrhea, pain syndrome with adnexitis, proctitis, colic (biliary and renal), pain syndrome with infectious and inflammatory diseases of the ENT -organs.

Tradename:

Diclac Retard

* Compound: Each tablet contains:

1- Diclofenac sodium 75 mg

2- Diclofenac sodium 150 mg

* Auxiliary components: lactose monohydrate, calcium hydrogen phosphate dihydrate, corn starch, methylhydroxypropyl cellulose, microcrystalline cellulose, sodium starch glycolate, colloidal silicon dioxide, magnesium stearate, iron oxide red (E172).

* Properties: NSAIDs, a derivative of phenylacetic acid. It has a pronounced anti-inflammatory, analgesic and moderate antipyretic effect. The mechanism of action is associated with inhibition of the activity of COX - the main enzyme of the metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. The analgesic effect is due to two mechanisms: peripheral (indirectly, through the suppression of prostaglandin synthesis) and central (due to inhibition of prostaglandin synthesis in the central and peripheral nervous system).

Inhibits the synthesis of proteoglycan in cartilage.

In rheumatic diseases, it reduces pain in the joints at rest and during movement, as well as morning stiffness and swelling of the joints, and increases the range of motion. Reduces post-traumatic and postoperative pain, as well as inflammatory edema.

Suppresses platelet aggregation. With prolonged use, it has a desensitizing effect.

* Indications: Articular syndrome (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout) Pain in the spine, neuralgia, myalgia, arthralgia, pain syndrome and inflammation after operations and injuries, pain syndrome with gout, migraine, algomenorrhea, pain syndrome with adnexitis, proctitis, colic (biliary and renal), pain syndrome with infectious and inflammatory diseases of the ENT -organs.

* Method of application and dose: Take 1-2 tablets per day.

The maximum daily dose for adults when taken orally is 150 mg / day.

Tablets should be taken before meals.

* Contraindications: Erosive and ulcerative lesions of the gastrointestinal tract in the acute phase, aspirin triad, hematopoietic disorders of unknown etiology, hypersensitivity to diclofenac or other NSAIDs.

* Precautionary measures: It is used with extreme caution in diseases of the liver, kidneys, gastrointestinal tract in history, dyspepsia, bronchial asthma, arterial hypertension, heart failure, immediately after major surgical interventions, as well as in elderly patients.

With a history of allergic reactions to NSAIDs and sulfites, diclofenac is used only in urgent cases. In the process of treatment, systematic monitoring of liver and kidney function, peripheral blood patterns is necessary.

* Side effects: From the digestive system: nausea, vomiting, anorexia, pain and discomfort in the epigastric region, flatulence, constipation, diarrhea; in some cases - erosive and ulcerative lesions, bleeding and perforation of the gastrointestinal tract; rarely - a violation of liver function. With rectal administration, in isolated cases, inflammation of the colon with bleeding, exacerbation of ulcerative colitis were noted.

From the side of the central nervous system and peripheral nervous system: dizziness, headache, agitation, insomnia, irritability, fatigue; rarely - paresthesia, visual disturbances (vagueness, diplopia), tinnitus, sleep disorders, convulsions, irritability, tremor, mental disorders, depression.

On the part of the hematopoietic system: rarely - anemia, leukopenia, thrombocytopenia, agranulocytosis.

From the urinary system: rarely - impaired renal function; edema may occur in predisposed patients.

Dermatological reactions: rarely - hair loss.

Allergic reactions: skin rash, itching; when used in the form of eye drops - itching, redness, photosensitivity.

* Storage method: At a temperature not higher than 30 degrees. In a dry place.

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