Hibiotic - 228.5mg/5ml Powder For Suspension 60ml

Treatment of infectious and inflammatory diseases caused by susceptible pathogens:

— infections of the lower respiratory tract (bronchitis, pneumonia, pleural empyema, lung abscess)

— infections of ENT organs (sinusitis, tonsillitis, otitis media)

— infections of the genitourinary system and pelvic organs (pyelonephritis, pyelitis, cystitis, urethritis, prostatitis, cervicitis, salpingitis, salpingo-oophoritis, tubo-ovarian abscess, endometritis, bacterial vaginitis, septic abortion, postpartum sepsis, pelvic peritonitis, soft chancre, gonorrhea)

— infections of the skin and soft tissues (erysipelas, impetigo, secondarily infected dermatoses, abscess, phlegmon, wound infection)

— osteomyelitis

— Postoperative infections. Prevention of infections in surgery

Tradename: Hibiotic

* Compound: Each 5 ml of the finished suspension contains:

Amoxicillin 200 mg

Clavulanic acid 28.5 mg

* Method of application and dose: The drug is taken orally.

The dosage regimen is set individually depending on the age, body weight, kidney function of the patient, as well as the severity of the infection.

For optimal absorption and to reduce possible digestive side effects, Hibiotic® is recommended to be taken at the start of a meal.

The minimum course of antibiotic therapy is 5 days.

Treatment should not be continued for more than 14 days without a review of the clinical situation.

For children from 3 months to 12 years:

Multiplicity of reception - 2 times / day

Suspension 200 mg/28.5 mg in 5 ml:

Low doses 25 mg/3.6 mg/kg/day

High doses 45 mg/6.4 mg/kg/day

Low doses of Hibiotic® are used to treat infections of the skin and soft tissues, as well as recurrent tonsillitis.

High doses of Hibiotic® are used to treat conditions such as otitis media, sinusitis, lower respiratory and urinary tract infections, bone and joint infections.

* Contraindications: Hypersensitivity to the components of the drug (including cephalosporins and other beta-lactam antibiotics); infectious mononucleosis (including with the appearance of a measles-like rash); phenylketonuria; episodes of jaundice or impaired liver function as a result of the use of amoxicillin / clavulanic acid in history; CC less than 30 ml / min (for tablets 875 mg / 125 mg).

Carefully:

Pregnancy, lactation, severe liver failure, gastrointestinal diseases (including a history of colitis associated with the use of penicillins), chronic renal failure.

Precautionary measures: During the course of treatment, it is necessary to monitor the state of the function of the hematopoietic organs, liver and kidneys.

In order to reduce the risk of side effects from the gastrointestinal tract, the drug should be taken with food.

Perhaps the development of superinfection due to the growth of microflora insensitive to it, which requires a corresponding change in antibiotic therapy.

May give false positive results in the determination of glucose in the urine. In this case, it is recommended to use a glucose oxidant method for determining the concentration of glucose in the urine.

In patients with hypersensitivity to penicillins, cross-allergic reactions with cephalosporin antibiotics are possible.

* Side effects: On the part of the digestive system: nausea, vomiting, diarrhea, gastritis, stomatitis, glossitis, increased activity of hepatic transaminases, in rare cases - cholestatic jaundice, hepatitis, liver failure (more often in the elderly, men, with long-term therapy), pseudomembranous and hemorrhagic colitis ( may also develop after therapy), enterocolitis, black hairy tongue, darkening of tooth enamel.

On the part of the hematopoietic organs: a reversible increase in prothrombin time and bleeding time, thrombocytopenia, thrombocytosis, eosinophilia, leukopenia, agranulocytosis, hemolytic anemia.

From the nervous system: dizziness, headache, hyperactivity, anxiety, behavioral changes, convulsions.

Local reactions: in some cases - phlebitis at the site of intravenous injection.

Allergic reactions: urticaria, erythematous rashes, rarely - exudative erythema multiforme, anaphylactic shock, angioedema, extremely rarely - exfoliative dermatitis, malignant exudative erythema (Stevens-Johnson syndrome), allergic vasculitis, a syndrome similar to serum sickness, acute generalized exanthematous pustulosis .

Others: candidiasis, development of superinfection, interstitial nephritis, crystalluria, hematuria.

* Storage method: At a temperature not higher than 30 degrees. Once opened and diluted, store refrigerated and use within 7 days.

* Package: The cardboard box contains the powder for the preparation of the suspension and a glass bottle, paper instructions.

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