Xithrone - 500 mg 1 Ampoule

Infectious and inflammatory diseases caused by microorganisms sensitive to the drug:

— infections of the upper respiratory tract and ENT organs: pharyngitis, tonsillitis, sinusitis, otitis media

— infections of the lower respiratory tract: acute bronchitis, exacerbation of chronic bronchitis, pneumonia, incl. caused by atypical pathogens

— infections of the skin and soft tissues: acne vulgaris of moderate severity, erysipelas, impetigo, secondarily infected dermatoses

— the initial stage of Lyme disease (borreliosis)

— migrating erythema (erythema migrans)

— urinary tract infections caused by Chlamydia trachomatis (urethritis, cervicitis)

Tradename:

Xithrone

* Compound: Each ampoule contains:

Azithromycin 500 mg

* Auxiliary components: sodium hydroxide

* Properties: A broad-spectrum antibacterial drug from the group of azalide macrolides, acts bacteriostatically. By binding to the 50S subunit of ribosomes, it inhibits the peptide translocase at the translation stage, inhibits protein synthesis, slows down the growth and reproduction of bacteria, and in high concentrations has a bactericidal effect. It acts on extra- and intracellularly located pathogens.

* Indications: Infectious and inflammatory diseases caused by microorganisms sensitive to the drug:

- infections of the upper respiratory tract and ENT organs: pharyngitis, tonsillitis, sinusitis, otitis media

- infections of the lower respiratory tract: acute bronchitis, exacerbation of chronic bronchitis, pneumonia, incl. caused by atypical pathogens

- infections of the skin and soft tissues: acne vulgaris of moderate severity, erysipelas, impetigo, secondarily infected dermatoses

- the initial stage of Lyme disease (borreliosis) - migratory erythema (erythema migrans)

- urinary tract infections caused by Chlamydia trachomatis (urethritis, cervicitis)

* Method of application and dose: Adults (including the elderly) and children over 12 years old weighing over 45 kg For infections of the upper and lower respiratory tract, ENT organs, skin and soft tissues: 500 mg 1 time / day for 3 days (course dose - 1.5 g).

* Contraindications: - severe liver and / or kidney failure

- children under 12 years of age weighing less than 45 kg (for this dosage form)

- breast-feeding

- simultaneous reception with ergotamine and dihydroergotamine

- hypersensitivity to macrolide antibiotics

Precautions - moderate impairment of liver and kidney function

- with arrhythmias or predisposition to arrhythmias and prolongation of the QT interval

- with the combined use of terfenadine, warfarin, digoxin

* Precautionary measures: If an antibiotic is missed, the missed dose should be taken as soon as possible and subsequent doses should be taken 24 hours apart.

After discontinuation of azithromycin therapy, hypersensitivity reactions in some patients may persist for a long time and may require specific therapy under medical supervision.

Side effects: From the digestive system: nausea, vomiting, diarrhea, abdominal pain, loose stools, flatulence, indigestion, anorexia, constipation.

Allergic reactions: itching, skin rashes, angioedema, urticaria.

From the side of the cardiovascular system: palpitations, arrhythmia, ventricular tachycardia.

Storage method: Store at a temperature not exceeding 30 degrees.

Package: Each carton contains 1 vial and paper instructions.

Manufacturer: Amon, Egypt

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